The best month to fly between Madrid and Brussels is February and the most expensive month to fly is November. (Average prices, based on 347 datapoints.)
The best day to arrive at Madrid is Tuesday and it would be best to avoid Sunday, as prices are on average 170.84% higher than on Tuesday. (Average prices, based on 216 datapoints.)
The cheapest airline flying from Madrid to Brussels is Iberia Airlines. They are 25% cheaper than Brussels Airlines. (Average prices, based on 355 datapoints.)
The best time to fly is at around 10. (Average prices, based on 550 datapoints.)