Please be aware that Tokyo and Osaka has multiple airports and that these results are for all airports serving the city.
The best month to fly between Tokyo and Osaka is November and the most expensive month to fly is August. (Average prices, based on 1069 datapoints.)
The best day to arrive at Tokyo is Wednesday and it would be best to avoid Tuesday, as prices are on average 34.73% higher than on Wednesday. (Average prices, based on 4388 datapoints.)
The cheapest airline flying from Tokyo to Osaka is Peach Aviation. They are 57% cheaper than Japan Airlines. (Average prices, based on 1095 datapoints.)
The best time to fly is at around 6. (Average prices, based on 2374 datapoints.)