Flight Istanbul Atatürk Airport departs from Istanbul Istanbul Atatürk Airport at 06:00 and arrives at Tashkent International Airport at 12:30.
The flighttime is about 4h 30m. The distance travelled ("as the bird flies"): 4500 Km. So the average speed is roughly 1000 Km.
There is an 2 hour time difference between Istanbul and Tashkent