Please be aware that Osaka and Tokyo has multiple airports and that these results are for all airports serving the city.
The best month to fly between Osaka and Tokyo is September and the most expensive month to fly is January. (Average prices, based on 387 datapoints.)
The best day to arrive at Osaka is Wednesday and it would be best to avoid Monday, as prices are on average 49.55% higher than on Wednesday. (Average prices, based on 237 datapoints.)
The cheapest airline flying from Osaka to Tokyo is Peach Aviation. They are 85% cheaper than ANA Wings. (Average prices, based on 418 datapoints.)
The best time to fly is at around 17. (Average prices, based on 1601 datapoints.)