Flight Tocumen International Airport departs from Panama City Tocumen International Airport at 19:30 and arrives at Havana José Marti International Airport at 23:10.
The flighttime is about 2h 40m. The distance travelled ("as the bird flies"): 414 Km. So the average speed is roughly 155 Km.
There is an 1 hour time difference between Panama City and Havana