Flight Sheremetyevo International Airport departs from Moscow Sheremetyevo International Airport at 08:15 and arrives at Tashkent International Airport at 14:10.
The flighttime is about 3h 55m. The distance travelled ("as the bird flies"): 3653 Km. So the average speed is roughly 933 Km.
There is an 2 hour time difference between Moscow and Tashkent